Incidence of hepatitis C among people who inject drugs in Ireland

Incidence of hepatitis C among people who inject drugs in Ireland

Background: Comprehensive information on the incidence and duration of hepatitis C virus (HCV) infection for people who inject drugs (PWID) in Ireland is not available. We created an incidence curve of injecting drug use in Ireland and subsequently estimated incidence of hepatitis C virus (HCV) infection. Methods: Anonymised data from the National Drug Treatment Reporting System (NDTRS) were us...

Hepatitis C virus vaccines among people who inject drugs.

Most people who inject drugs (PWID) are infected with hepatitis C virus (HCV), and PWID have the highest risk of HCV infection of any risk group. The incidence of HCV infection is 5%-25% per year, demonstrating continued need for HCV infection prevention in PWID. Existing data in chimpanzees and PWID suggest that protective immunity against persistent HCV infection is achievable. Due to the hig...

to new hepatitis C therapies for people who inject drugs

Modelling the burden of hepatitis C infection among people who inject drugs in Norway, 1973–2030

BACKGROUND Lack of Hepatitis C virus (HCV) incidence data in (Norwegian) high-risk groups impedes the ability to make informed decisions on prevention measures. Thus we rely on modelling to estimate the incidence and burden of HCV infections. METHODS We constructed a compartmental model for HCV infections in Norway among active and former people who inject drugs (PWIDs). We based yearly trans...

Geographic Differences in Temporal Incidence Trends of Hepatitis C Virus Infection Among People Who Inject Drugs: The InC3 Collaboration

Background We determined temporal trends (1985-2011) in hepatitis C virus (HCV) incidence and associated behavioral exposures for people who inject drugs (PWID) from the United States (Boston, Baltimore, and San Francisco), Canada (Montreal), the Netherlands (Amsterdam), and Australia (Sydney and Melbourne). Methods Using population-based cohort data from HCV-negative PWID, we calculated over...